Pharmacologic treatments for pediatric bipolar disorder: A review and meta-analysis. Algorithms for medication decisions are briefly reviewed. Available data suggests that lithium, some anticonvulsants and second-generation antipsychotics may be equally beneficial in the acute monotherapy for youth with mixed or manic states. 2010 Mar;12(2):164-71. doi: 10.1111/j.1399-5618.2010.00791.x. Day treatment programs. Author information: (1)Pediatric Psychopharmacology Program, Division of Child Psychiatry, Massachusetts General Hospital, Boston, Massachusetts. Despite recent developments in understanding the phenomenology of PBD and in identifying pharmacologic and psychosocial interventions, critical gaps remain. Bipolar disorder is a lifelong illness … Objective. The existence of a mood disorder in adults involving severe mood swings from states of deep depression to states of elation has been recognized now for over a century. This is a systematic chart review of all outpatient youth with the diagnosis of bipolar disorder and bipolar spectrum disorder treated with aripiprazole either alone or as add-on to ongoing treatments. A.}". Psychopharmacology of pediatric bipolar disorders in children and adolescents. RATIONALE: Pediatric bipolar disorder (PBD) is a chronic and debilitating psychiatric illness. @article{c35361e815cb44f78fdc313729866691. Conclusions: A substantial body of scientific literature has evaluated the safety and efficacy of various medicines and drug classes in the treatment of mania in pediatric bipolar disorder. Existing psychosocial treatments and the evidence for those treatments are also reviewed. Read honest and unbiased product reviews from our users. abstract = "The aim of this study was to review the diagnosis and the pharmacologic and psychosocial interventions for pediatric bipolar disorder (PBD). An evidence-based assessment protocol for PBD is reviewed. N2 - The aim of this study was to review the diagnosis and the pharmacologic and psychosocial interventions for pediatric bipolar disorder (PBD). A. Heil. The evidence for the following three categories of pharmacologic interventions are reviewed: Lithium, antiepileptics, and second generation antipsychotics. To inform clinicians treating psychiatric disorders in pediatric patients, we have summarized the neuropharmacology, pharmacokinetics, clinical trial experience, and clinical use of asenapine in pediatric patients. To review the literature of the past decade covering the epidemiology, clinical characteristics, assessment, longitudinal course, biological and psychosocial correlates, and treatment and prevention of pediatric bipolar disorder (BD). In the past decade, interest in and research on pediatric bipolar disorder (BD) has increased substantially. Hence, most children and adolescents with this diagnosis require referral to a psychiatrist specializing in their age group. and West, {A. E.} and Heil, {J. The evidence for the following three categories of pharmacologic interventions are reviewed: Lithium, antiepileptics, and second generation antipsychotics. Epub 2018 Dec 19. 2007;8(1):4-11. doi: 10.1080/15622970601083280. N2 - The aim of this study was to review the diagnosis and the pharmacologic and psychosocial interventions for pediatric bipolar disorder (PBD). Rationale: A context for understanding controversies and difficulties in the diagnosis of PBD is provided. keywords = "Bipolar disorder, Child, Mental disorders". Existing psychosocial treatments and the evidence for those treatments are also reviewed.  |  Asenapine Treatment in Pediatric Patients with Bipolar I Disorder or Schizophrenia: A Review. NIH Psychopharmacology (Berl). Continued treatment. 12, 13 Concerns over the diagnosis of PBD stem from disagreements over what symptoms constitute PBD. A comprehensive literature review of studies discussing the diagnosis and treatment of PBD was conducted. In pediatric BD, the rate of attempted suicide is 40 times that of healthy adolescents, 2 and BD is the diagnosis imparting the greatest risk for completed suicide. Treatment of pediatric bipolar disorder: A review. Pediatric bipolar disorder (PBD) is a chronic and debilitating psychiatric illness. To inform clinicians treating psychiatric disorders in pediatric patients, we have summarized the neuropharmacology, pharmacokinetics, clinical trial experience, and clinical use of asenapine in pediatric patients. Meta-analyses of randomized … Other aspects of pediatric bipolar disorder are discussed separately, including the general principles of using pharmacotherapy; efficacy, administration, and side effects of second-generation antipsychotics for mania; efficacy and core elements of adjunctive psychotherapy; assessment and diagnosis; and the … Physical exam. Pharmacological and non-drug treatment of child bipolar I disorder during prospective eight-year follow-up. However, pediatric bipolar disorder is often not recognized, and many youth with the disorder do not receive treatment or are treated for comorbid conditions rather than bipolar disorder . HHS 2016 Spring;10(2):16-25. Epub 2018 May 29. Objective: Little is known about the treatment of psychiatric comorbidities in bipolar disorder. Comparison of aripiprazole and other atypical antipsychotics for pediatric bipolar disorder: a retrospective chart review of efficacy and tolerability. Conclusion: We review data elucidating the pathophysiology of pediatric BD, with a focus on how these results may inform diagnosis. -, J Am Acad Child Adolesc Psychiatry. You may also fill out a psychological self-assessment or questionnaire. People who skip maintenance treatment are at high risk of a relapse of symptoms or having minor mood changes turn into full-blown mania or depression. Results of 2 small open-label studies have recently been published that suggest beneficial effects of v-3s in both phases of pediatric bipolar disorder. RationalePediatric bipolar disorder (PBD) is a chronic and debilitating psychiatric illness. Epub 2013 Aug 26. 7, 27. Prevalence rates of the disorder have doubled in outpatient settings, while twice as many research articles on pediatric BD were published in the past five years as in the prior decade. -, J Child Adolesc Psychopharmacol. N2 - Risperidone is a commonly used medication for the treatment of bipolar disorder and schizophrenia in children and adolescents. A. PY - 2011/3. Epub 2011 Jul 13. Vaudreuil CAH(1)(2), Faraone SV(3), Di Salvo M(1), Wozniak JR(1)(2), Wolenski RA(1), Carrellas NW(1), Biederman J(1)(2). This topic reviews the choice of treatment for pediatric bipolar disorder. This disorder is commonly referred to as manic-depression but is now formally referred to as bipolar disorder, referring to the two “poles” of depression and mania. T1 - Treatment of pediatric bipolar disorder. For these reasons, there is a need for effective treatment for PBD. However, concerns remain as to the inadequacy of the extant literature on its pharmacotherapy. A context for understanding controversies and difficulties in the diagnosis of PBD is provided. Evidence-based Treatments Pharmacological Treatments Psychosocial Treatments Unproven Treatments Cultural Considerations Introduction In recent years, there has been an explosion of interest among researchers and clinicians in the assessment, definition, diagnosis, and treatment of pediatric bipolar disorder (PBD). Psychiatry and Behavioral Sciences; Research output: Contribution to journal › Review article › peer-review. AU - Bishop, Jeffrey R. AU - Pavuluri, Mani N. PY - 2008/4/7. author = "Washburn, {J. Howard Y. Liu, Mona P. Potter, K. Yvonne Woodworth, Dayna M. Yorks, Carter R. Petty, Janet R. Wozniak, Stephen V. Faraone, Joseph Biederman As pediatric bipolar (BP) disorder tends to evolve over time, some youth may present to clinical attention with insufficient symptoms to fulfill full diagnostic criteria for a diagnosis of BP disorder. Prevalence rates of the disorder have doubled in outpatient settings, while twice as many research articles on pediatric BD were published in the past five years as in the prior decade. Pediatric bipolar disorder (PBD) is a chronic and debilitating psychiatric illness. The evidence for the following three categories of pharmacologic interventions are reviewed: Lithium, antiepileptics, and second generation antipsychotics. Pediatric bipolar diorder is a serious neuropsychiatric disorder asociated with high levels of morbidity and disabilty. Treatment of pediatric bipolar disorder: A review. publisher = "Edizioni Minerva Medica S.p.A.". Oh J, Chang JG, Lee SB, Song DH, Cheon KA. T1 - Review of risperidone for the treatment of pediatric and adolescent bipolar disorder and schizophrenia. Iran J Child Neurol. J Am Acad Child Adolesc Psychiatry. OBJECTIVE: A growing body of literature has documented pediatric bipolar disorder to be a severely impairing form of psychopathology. 2000 Sep;57(9):841-9 Journal of the American Academy of Child and Adolescent Psychiatry . Method There is limited evidence from double-blind, placebo-controlled trials regarding the treatment of PBD. Psychiatric assessment. N2 - Risperidone is a commonly used medication for the treatment of bipolar disorder and schizophrenia in children and adolescents. Few studies have evaluated the effects of antimanic agents in children younger than 10 years. A context for understanding controversies and difficulties in the diagnosis of PBD is provided. This review focuses on recent developments in the study of pediatric BD. Bipolar disorders are common, disabling, recurrent mental health conditions of variable severity. 2011 Aug;50(8):749-62.e39. Asenapine Treatment in Pediatric Patients With Bipolar I Disorder or Schizophrenia: A Review. Psychopharmacology of pediatric bipolar disorder: a review. In the past decade, interest in and research on pediatric bipolar disorder (BD) has increased substantially. Treatment of pediatric bipolar disorder : A review. To suggest directions for future research. The aim of this study was to review the diagnosis and the pharmacologic and psychosocial interventions for pediatric bipolar disorder (PBD). World J Biol Psychiatry. -. The comprehensive treatment of bipolar disorder, like all other mental illnesses in children and adolescents, involves a multi-modal approach. 1997 Sep;36(9):1168-76 Pediatric Bipolar Disorder. 2. Pediatr Clin North Am. An evidence-based assessment protocol for PBD is reviewed. Geller B, Tillman R, Bolhofner K, Zimerman B. Bipolar Disord. Overview; Fingerprint; Fingerprint Dive into the research topics of 'Treatment of pediatric bipolar disorder: A review'. In general, a team approach is used in the clinical setting because several factors need to be addressed, including medication, family issues, social and school functioning, and, when present, substance abuse. 2011. Also, very few studies have addressed the treatment of comorbidities and maintenance/relapse prevention in PBD. There is very limited data on the treatment of the depressed phase of bipolar illness in the youth. RATIONALE: Pediatric bipolar disorder (PBD) is a chronic and debilitating psychiatric illness. Although significant progress was made in the treatment of youth with bipolar disorder, there is a need for more methodologically stringent research to more precisely define evidence-based treatment strategies for PBD. A context for understanding controversies and difficulties in the diagnosis of PBD is provided. 2018 Oct 1;238:147-155. doi: 10.1016/j.jad.2018.05.063. Y1 - 2008/4/7. 19 Scopus citations. It is associated with many short-term and long-term complications including poor academic and social performance, legal problems and increased risk of suicide. Pediatric bipolar disorder (PBD) is a chronic and debilitating psychiatric illness. Furthermore, treatment studies have not been systematically reviewed for treatment effects on core and associated symptoms. 2011 Feb;58(1):173-87, xii. OBJECTIVE A growing body of literature has documented pediatric bipolar disorder to be a severely impairing form of psychopathology. By continuing you agree to the use of cookies. Other disorders have symptoms like those of bipolar disorder, including ADHD, disruptive mood regulation disorder, oppositional defiant disorder, conduct disorder, and anxiety disorders. Title:Psychopharmacologic Treatment of Children and Adolescents with Bipolar Disorder: A Review VOLUME: 5 ISSUE: 1 Author(s):Dana Baker Kaplin, Alison Conca-Cheng and Robert L. 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